Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis orvascular malformations represent abnormal collections of blood vessels. In this category are found arteriovenous malformations, cavernous hemangiomas, telangiectesis and venous angiomas. Of these, arteriovenous malformations and cavernous hemangiomas are the most likely to cause problems, such as intracranial hemorrhage, seizures, and focal or discrete neurologic deficits. Diagnosis is made by magnetic resonance imaging, computed tomography and arteriography. Surgical therapy may be required once these lesions become apparent. Aneurysms represent a weakening in the wall of a blood vessel, predisposing it to bleeding. Bleeding results in a subarachnoid hemorrhage that may be fatal or manifest only as a headache, with all intermediate points, including a stroke, being possible. Diagnosis of the hemorrhage is made by computed tomography. Arteriography is used to document the presence of an aneurysm and define its vascular anatomy. Surgery is generally required to repair the aneurysm after bleeding has occured, since there is a strong tendency to rebleed.